Methods and systems are provided for maintaining combustion stability in a multi-fuel engine. In one example, a system may include first and second fuel systems to deliver liquid and gaseous fuels, respectively, to at least one cylinder of the engine, and a controller. The controller may be configured to supply the gaseous fuel to the at least one cylinder, inject the liquid fuel to the at least one cylinder to compression ignite the liquid fuel and combust the gaseous fuel in the at least one cylinder, and retard an injection timing of the injection of the liquid fuel based on a measured parameter associated with auto-ignition of end gases subsequent to the compression-ignition of the liquid fuel. In some examples, the controller may further be configured to adjust an amount of the gaseous fuel relative to an amount of the liquid fuel based on the measured parameter.