The disclosure relates to a system and method of configuring and validating multi-vendor and multi-region Internet-of-Things (IoT) devices using reinforcement learning. In some embodiments, the method includes generating a matching table for each of a plurality of IoT sensors based on a plurality of sensor attributes extracted from a product data associated with an IoT sensor; acquiring an identification information and operational information associated with the IoT sensor and a set of neighboring IoT sensors for each of the plurality of IoT sensors; identifying an appropriate set of IoT sensors from the plurality of IoT sensors, based on a user requirement, the matching table, the identification information and the operational information, using a Reinforcement Learning (RL) model; and dynamically configuring each of the appropriate set of IoT sensors based on a vendor type.