Analog signal measurement and related circuitry, systems, and methods are disclosed. Circuitry includes timing circuitry configured to assert a first enable signal at a first time and a second enable signal at a second time. The circuitry also includes an operational amplifier circuit configured to enable responsive to the assertion of the first enable signal. The operational amplifier circuit is configured to receive an analog input signal and, if enabled, generate an amplified analog input signal responsive to the analog input signal. The circuitry further includes signal analyzing circuitry configured to enable responsive to the assertion of the first enable signal, compare the amplified analog input signal to one or more threshold values responsive to the assertion of the second enable signal, and generate an alert signal responsive to a determination that the amplified analog input signal falls outside of the one or more threshold values.