The embodiment of the present disclosure provides a back-to-source relationship management system, method, apparatus, server and storage medium. The back-to-source relationship management system comprises a back-to-source relationship management server, which is configured for obtaining a target domain name corresponding to a target CDN node back-to-source relationship to be adjusted and adjustment information; using the adjustment information to adjust the target CDN node back-to-source relationship to obtain the adjusted target CDN node back-to-source relationship; synchronizing the target domain name and the adjusted target CDN node back-to-source relationship to a cache management server; the cache management server is configured for receiving the target domain name and the adjusted target CDN node back-to-source relationship; using the adjusted target CDN node back-to-source relationship to update the CDN node back-to-source relationship corresponding to the target domain name and obtain a new CDN node back-to-source relationship.