A method (300) for detecting one or more caries using an imaging device (10), the method including the steps of: (i) directing (320) light from a first light source (12) toward a tooth (40); (ii) measuring (340), with an optical sensor (16), transmission of light from the first light source through the tooth; (iii) directing (330) light from a second light source (14) toward the tooth, wherein the second light source directs light at the tooth at a different angle relative to the first light source; (iv) measuring (350), with the optical sensor, reflectance from the tooth of light from the second light source; (v) comparing (360) the measured transmission to the measured reflectance; and (vi) determining (370), based at least in part on said comparison, whether a caries is present in the tooth.