Invention Grant
- Patent Title: Encased tamper resistant controlled release dosage forms
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Application No.: US17185221Application Date: 2021-02-25
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Publication No.: US11590082B2Publication Date: 2023-02-28
- Inventor: Haiyong Hugh Huang
- Applicant: Purdue Pharma L.P.
- Applicant Address: US CT Stamford
- Assignee: Purdue Pharma L.P.
- Current Assignee: Purdue Pharma L.P.
- Current Assignee Address: US CT Stamford
- Agency: Lowenstein Sandler LLP
- Main IPC: A61K9/20
- IPC: A61K9/20 ; A61K9/24 ; A61K31/485 ; A61K9/00 ; A61K9/28

Abstract:
In certain embodiments, the present invention is directed to a solid controlled release dosage form comprising: a core comprising a first portion of an opioid analgesic dispersed in a first matrix material; and a shell encasing the core and comprising a second portion of the opioid analgesic dispersed in a second matrix material; wherein the amount of opioid analgesic released from the dosage form is proportional within 20% to elapsed time from 8 to 24 hours, as measured by an in-vitro dissolution in a USP Apparatus 1 (basket) at 100 rpm in 900 ml simulated gastric fluid without enzymes (SGF) at 37 C.
Public/Granted literature
- US20210251907A1 Encased Tamper Resistant Controlled Release Dosage Forms Public/Granted day:2021-08-19
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