Invention Grant
- Patent Title: Asenapine-containing adhesive patch
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Application No.: US17281623Application Date: 2019-09-25
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Publication No.: US11590106B2Publication Date: 2023-02-28
- Inventor: Masaki Yukuhiro , Yuka Takagi , Yasunari Michinaka
- Applicant: Hisamitsu Pharmaceutical Co., Inc.
- Applicant Address: JP Tosu
- Assignee: Hisamitsu Pharmaceutical Co., Inc.
- Current Assignee: Hisamitsu Pharmaceutical Co., Inc.
- Current Assignee Address: JP Tosu
- Agency: Wolf, Greenfield & Sacks, P.C.
- Priority: JPJP2018-186876 20181001
- International Application: PCT/JP2019/037586 WO 20190925
- International Announcement: WO2020/071207 WO 20200409
- Main IPC: A61K31/407
- IPC: A61K31/407 ; A61K9/70 ; A61K47/02 ; A61K47/12 ; A61K47/32

Abstract:
An object of the present invention is to provide an asenapine-containing patch having excellent sustained-release properties while enhancing skin permeability by using a silicone-based pressure-sensitive adhesive base. The present invention relates to a patch having a support and a pressure-sensitive adhesive layer, wherein the pressure-sensitive adhesive layer comprises asenapine and/or a pharmaceutically acceptable salt thereof, a silicone-based pressure-sensitive adhesive base and a release control agent, and the ratio of the maximum skin permeation rate of asenapine to the minimum skin permeation rate from the time when the maximum skin permeation rate is reached to 24 hours is less than 1.62.
Public/Granted literature
- US20210393587A1 ASENAPINE-CONTAINING ADHESIVE PATCH Public/Granted day:2021-12-23
Information query
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