Invention Grant
- Patent Title: Biodegradable, antioxidant, thermally responsive injectable hydrogel and uses therefor
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Application No.: US16336994Application Date: 2017-10-06
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Publication No.: US11590162B2Publication Date: 2023-02-28
- Inventor: William R. Wagner , Yasumoto Matsumura , Murugesan Velayutham , Yang Zhu
- Applicant: University of Pittsburgh—Of the Commonwealth System of Higher Education
- Applicant Address: US PA Pittsburgh
- Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
- Current Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
- Current Assignee Address: US PA Pittsburgh
- Agency: The Webb Law Firm
- International Application: PCT/US2017/055564 WO 20171006
- International Announcement: WO2018/067948 WO 20180412
- Main IPC: A61K31/74
- IPC: A61K31/74 ; A61K31/79 ; A61K9/00 ; C08F290/06 ; A61L31/14 ; C08F220/54 ; C08F299/04

Abstract:
Provided herein are antioxidant, thermally-responsive copolymer-based compositions and methods of making and using the compositions, e.g., for treatment of ischemia reperfusion injury in a patient. The copolymer comprises a hydrocarbyl backbone, and a plurality of pendant pyrrolidone, antioxidant radical, polyester oligomer, and N-alkyl amide groups.
Public/Granted literature
- US20190216847A1 Biodegradable, Antioxidant, Thermally Responsive Injectable Hydrogel and Uses Therefor Public/Granted day:2019-07-18
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