Invention Grant
- Patent Title: Chimeric antigen receptor
-
Application No.: US17723209Application Date: 2022-04-18
-
Publication No.: US11590170B2Publication Date: 2023-02-28
- Inventor: Martin Pulé , Evangelia Kokalaki , Shaun Cordoba , Shimobi Onuoha , Simon Thomas , Biao Ma , Mathieu Ferrari
- Applicant: AUTOLUS LIMITED
- Applicant Address: GB London
- Assignee: AUTOLUS LIMITED
- Current Assignee: AUTOLUS LIMITED
- Current Assignee Address: GB London
- Agency: Marshall, Gerstein & Borun LLP
- Priority: GB1807866 20180515,GB1809773 20180614
- Main IPC: A61K35/17
- IPC: A61K35/17 ; A61P35/00 ; C07K16/28
Abstract:
The present invention provides a chimeric antigen receptor (CAR) which binds a target antigen having a bulky extracellular domain, wherein the CAR comprises a Fab antigen binding domain. The present invention also provides nucleic acid sequences and constructs encoding such a CAR, cells expressing such a CAR and their therapeutic uses.
Public/Granted literature
- US20220257659A1 CHIMERIC ANTIGEN RECEPTOR Public/Granted day:2022-08-18
Information query
IPC分类:
