Invention Grant
- Patent Title: Methods and reagents for efficient and targeted delivery of therapeutic molecules to CXCR4 cells
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Application No.: US17026543Application Date: 2020-09-21
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Publication No.: US11590198B2Publication Date: 2023-02-28
- Inventor: Antonio Pedro Villaverde Corrales , Esther Vazquez Gomez , Maria Virtudes Cespedes Navarro , Isolda Casanova Rigat , Neus Ferrer Miralles , Ramon Mangues Bafalluy , Ugutz Unzueta Elorza
- Applicant: UNIVERSITAT AUTONOMA DE BARCELONA , INSTITUT RECERCA HOSPITAL DE LA SANTA CREU I SANT PAU , CENTRO DE INVESTIGACION BIOMEDICA EN RED EN BIOINGENIERIA BIOMATERIALES Y NANOMEDICINA (CIBER BBN)
- Applicant Address: ES Barcelona; ES Barcelona; ES Saragossa
- Assignee: UNIVERSITAT AUTONOMA DE BARCELONA,INSTITUT RECERCA HOSPITAL DE LA SANTA CREU I SANT PAU,CENTRO DE INVESTIGACION BIOMEDICA EN RED EN BIOINGENIERIA BIOMATERIALES Y NANOMEDICINA (CIBER BBN)
- Current Assignee: UNIVERSITAT AUTONOMA DE BARCELONA,INSTITUT RECERCA HOSPITAL DE LA SANTA CREU I SANT PAU,CENTRO DE INVESTIGACION BIOMEDICA EN RED EN BIOINGENIERIA BIOMATERIALES Y NANOMEDICINA (CIBER BBN)
- Current Assignee Address: ES Barcelona; ES Barcelona; ES Saragossa
- Agency: Greer, Burns & Crain Ltd.
- Priority: EP11382005 20110113
- Main IPC: A61K38/10
- IPC: A61K38/10 ; A61K47/62 ; A61K47/66 ; A61K47/00 ; C07K7/08 ; C07K14/00 ; C12N15/62 ; A61P31/14 ; A61P35/00 ; C07K14/435
Abstract:
Conjugates comprising a targeting moiety specific for the CXCR4 and based on the polyphemusin-derived peptide and a therapeutic or imaging agent are provided. Therapeutic and diagnostic methods with the conjugates which require specific targeting to CXCR4+cells are provided as well.
Public/Granted literature
- US20210008154A1 METHODS AND REAGENTS FOR EFFICIENT AND TARGETED DELIVERY OF THERAPEUTIC MOLECULES TO CXCR4 CELLS Public/Granted day:2021-01-14
Information query
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