Invention Grant
- Patent Title: Complex of gadolinium and a chelating ligand derived from a diastereoisomerically enriched PCTA and preparation and purification process
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Application No.: US17423638Application Date: 2020-01-17
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Publication No.: US11590246B2Publication Date: 2023-02-28
- Inventor: Soizic Le Greneur , Alain Chénedé , Martine Cerf , Myriam Petta , Emmanuelle Marais , Bruno François , Caroline Robic , Stéphanie Louguet
- Applicant: GUERBET
- Applicant Address: FR Villepinte
- Assignee: GUERBET
- Current Assignee: GUERBET
- Current Assignee Address: FR Villepinte
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, L.L.P.
- Priority: FR1900432 20190117
- International Application: PCT/EP2020/051153 WO 20200117
- International Announcement: WO2020/148436 WO 20200723
- Main IPC: A61K49/10
- IPC: A61K49/10
Abstract:
The present invention relates to a complex of formula (II) constituted of at least 90% of a diastereoisomeric excess comprising a mixture of isomers II-RRR and II-SSS of formulae: The present invention also relates to a process for preparing and purifying said complex of formula (II), and also to a composition comprising said complex.
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