Described herein are systems, methods, and computer readable media for capturing sensor data relating to an enclosed compartment of a vehicle (e.g., a cargo area of the vehicle) via one or more vehicle sensors; analyzing the sensor data to determine whether it is indicative of a living being present in the enclosed compartment; performing an object detection analysis on at least a portion of the sensor data to determine a type of living being detected; and initiating one or more automated vehicle response measures based on the type of living being.