Invention Grant
- Patent Title: Indoleamine-2,3-dioxygenase inhibitor, preparation method therefor and use thereof
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Application No.: US16967077Application Date: 2019-01-31
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Publication No.: US11591301B2Publication Date: 2023-02-28
- Inventor: Wu Du , Wen Ren , Haibin Lv , Haibo Li , Kun Wen , Jinyun He , Dekun Qin , Xinghai Li , Yuanwei Chen
- Applicant: HINOVA PHARMACEUTICALS INC.
- Applicant Address: CN Sichuan
- Assignee: HINOVA PHARMACEUTICALS INC.
- Current Assignee: HINOVA PHARMACEUTICALS INC.
- Current Assignee Address: CN Sichuan
- Agency: Novick, Kim & Lee, PLLC
- Agent Allen Xue
- Priority: CN201810107237.8 20180202
- International Application: PCT/CN2019/074274 WO 20190131
- International Announcement: WO2019/149255 WO 20190808
- Main IPC: C07D271/08
- IPC: C07D271/08 ; C07D413/12
Abstract:
A compound is represented by formula (I). A pharmaceutical composition contains the compound of formula (I). The compound is used in the preparation of an indoleamine-2,3-dioxygenase (IDO) inhibitor drug. The compound exhibits inhibition effect on IDO protease and metabolizes stably in the body. The compound or pharmaceutical composition thereof can be used for preparing an IDO inhibitor drug, and can also be used for preparing a drug for preventing and/or treating diseases having IDO-mediated tryptophan metabolic pathway pathological features.
Public/Granted literature
- US20210047281A1 INDOLEAMINE-2,3-DIOXYGENASE INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF Public/Granted day:2021-02-18
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