Invention Grant
- Patent Title: Substituted pyrazole-pyrimidines, variants thereof, and uses therefore
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Application No.: US17179705Application Date: 2021-02-19
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Publication No.: US11591315B2Publication Date: 2023-02-28
- Inventor: Ronald Charles Hawley , Prabha Ibrahim , Anthony P. Ford , Joel R. Gever
- Applicant: Afferent Pharmaceuticals, Inc.
- Applicant Address: US CA San Mateo
- Assignee: Afferent Pharmaceuticals, Inc.
- Current Assignee: Afferent Pharmaceuticals, Inc.
- Current Assignee Address: US CA San Mateo
- Agent Julie M. Lake; Catherine D. Fitch
- Main IPC: C07D403/12
- IPC: C07D403/12 ; C07D417/12 ; C07D403/06 ; A61P11/00 ; A61P11/06 ; A61P13/00 ; A61P29/00
Abstract:
Disclosed herein are substituted pyrazole-pyrimidine compounds of Formula I and variants thereof for the treatment, for example, of diseases associated with P2X purinergic receptors: In one embodiment, the P2X3 and/or P2X2/3 antagonists disclosed herein are potentially useful, for example, for the treatment of visceral organ, cardiovascular and pain-related diseases, conditions and disorders.
Public/Granted literature
- US20210171505A1 SUBSTITUTED PYRAZOLE-PYRIMIDINES, VARIANTS THEREOF, AND USES THEREFORE Public/Granted day:2021-06-10
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