Invention Grant
- Patent Title: Compounds and compositions including phosphorothioated oligodeoxynucleotide, and methods of use thereof
-
Application No.: US17010259Application Date: 2020-09-02
-
Publication No.: US11591596B2Publication Date: 2023-02-28
- Inventor: Marcin Tomasz Kortylewski , Piotr Marek Swiderski , Guido Marcucci , Bin Zhang , Ya-Huei Kuo
- Applicant: City of Hope
- Applicant Address: US CA Duarte
- Assignee: City of Hope
- Current Assignee: City of Hope
- Current Assignee Address: US CA Duarte
- Agency: Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C07H21/04 ; C12N15/113 ; A61K31/7004 ; A61K47/54 ; A61K31/704 ; A61K45/06 ; C12N15/11 ; A61K31/7125 ; A61P35/02 ; A61K31/506
Abstract:
The present disclosure relates to a compound including a nucleic acid sequence conjugated to an anti-microRNA or a microRNA-mimic or a compound including a modified anti-microRNA sequence, compositions of such a compound, and method of treatment of a disease, and method of suppressing microRNA activity by the disclosed compound or composition.
Public/Granted literature
- US20210115443A1 COMPOUNDS AND COMPOSITIONS INCLUDING PHOSPHOROTHIOATED OLIGODEOXYNUCLEOTIDE, AND METHODS OF USE THEREOF Public/Granted day:2021-04-22
Information query
