Method of making and using mammalian liver cells for treating hemophilia or lysosomal storage disorder

Invention Grant

US11591622B2 Method of making and using mammalian liver cells for treating hemophilia or lysosomal storage disorder 有权

Patent Title: Method of making and using mammalian liver cells for treating hemophilia or lysosomal storage disorder
Application No.: US16531749

Application Date: 2019-08-05
Publication No.: US11591622B2

Publication Date: 2023-02-28
Inventor: Michael C. Holmes , Thomas Wechsler
Applicant: Sangamo Therapeutics, Inc.
Applicant Address: US CA Richmond
Assignee: Sangamo Therapeutics, Inc.
Current Assignee: Sangamo Therapeutics, Inc.
Current Assignee Address: US CA Richmond
Agency: Foley & Lardner LLP
Main IPC: A61K48/00
IPC: A61K48/00 ; C12N15/90 ; C12N15/85

Abstract:

Disclosed herein are methods and compositions for targeted, nuclease-mediated insertion of transgene sequences into the genome of a cell.

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IPC分类:

A	人类生活必需
A61	医学或兽医学；卫生学
A61K	医用、牙科用或梳妆用的配制品（专门适用于将药品制成特殊的物理或服用形式的装置或方法A61J3/00；空气除臭，消毒或灭菌，或者绷带、敷料、吸收垫或外科用品的化学方面，或材料的使用入A61L；肥皂组合物入C11D）
A61K48/00	含有插入到活体细胞中的遗传物质以治疗遗传病的医药配制品；基因治疗