In a wireless communication network, a user Centralized Unit (CU) exchanges test data with user Distributed Units (DUs). The user DUs wirelessly exchange the test data with access DUs in wireless Access Points (APs). The access DUs exchange the test data with access CUs in the wireless APs. The user CU estimates data throughputs based on the test data for combinations of the user DUs, the access DUs, and the access CUs. The user CU selects a combination based on the estimated data throughputs. The user CU exchanges user data with the user communication devices and exchanges the user data with the user DUs in the selected combination. The user DUs in the selected combination wirelessly exchange the user data with the access DUs in the selected combination. The access DUs in the selected combination exchange the user data with the access CUs in the selected combination.