Systems and methods for measurement of end tidal carbon dioxide, including a device having a body and a tubular gas line. The body is adapted to be attached to a patient airway and has a first gas line securing portion which has an aperture through it and is adapted to secure the gas line to the body. The tubular gas line is secured in the aperture. The tubular gas line has a proximal portion extending from a proximal end of the aperture and has a proximal end which is adapted to be connected to an end tidal CO2 monitor. The tubular gas line also has a distal portion extending from a distal end of the aperture and having a distal end which provides an inlet for end tidal CO2 exhaled by a patient.