Invention Grant
- Patent Title: Marburgvirus consensus antigens, nucleic acid constructs and vaccines made therefrom, and methods of using same
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Application No.: US16465691Application Date: 2017-12-01
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Publication No.: US11596678B2Publication Date: 2023-03-07
- Inventor: David Weiner , Ami Patel , Sarah Elliott
- Applicant: The Trustees of the University of Pennsylvania , THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY
- Applicant Address: US PA Philadelphia; US PA Philadelphia
- Assignee: The Trustees of the University of Pennsylvania,THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY
- Current Assignee: The Trustees of the University of Pennsylvania,THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY
- Current Assignee Address: US PA Philadelphia; US PA Philadelphia
- Agency: Riverside Law LLP
- International Application: PCT/US2017/064135 WO 20171201
- International Announcement: WO2018/102642 WO 20180607
- Main IPC: A61P31/14
- IPC: A61P31/14 ; C12N1/00 ; A61K39/12 ; A61P37/04 ; C07K14/005 ; A61K39/00
Abstract:
Nucleic acid molecules and compositions comprising one or more nucleic acid sequences that encode a consensus Marburgvirus filovirus glycoprotein immunogens. Immunomodulatory methods and methods of inducing an immune response against Marburgvirus are disclosed. Method of preventing infection by Marburgvirus and methods of treating individuals infected with Marburgvirus are disclosed. Consensus Marburgvirus filovirus glycoprotein immunogens are disclosed.
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