Invention Grant
- Patent Title: Stabilized formulations containing anti-IL-33 antibodies
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Application No.: US16825007Application Date: 2020-03-20
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Publication No.: US11596690B2Publication Date: 2023-03-07
- Inventor: Qingyan Hu , Dingjiang Liu
- Applicant: Regeneron Pharmaceuticals, Inc.
- Applicant Address: US NY Tarrytown
- Assignee: Regeneron Pharmaceuticals, Inc.
- Current Assignee: Regeneron Pharmaceuticals, Inc.
- Current Assignee Address: US NY Tarrytown
- Agency: Schwabe, Williamson & Wyatt PC
- Agent Lisa Dombach Flanagan
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K9/00 ; A61K47/12 ; A61K47/18 ; A61K47/26 ; A61M5/20 ; A61M5/32 ; C07K16/24 ; A61M5/178

Abstract:
The present invention provides pharmaceutical formulations comprising an antibody that specifically binds to human interleukin-33 (hIL-33). The formulations may contain, in addition to an anti-IL-33 antibody, a buffer, at least one amino acid, at least one sugar, or at least one non-ionic surfactant. The pharmaceutical formulations of the present invention exhibit a substantial degree of antibody stability after storage for several months and after being subjected to thermal and other physical stresses.
Public/Granted literature
- US20200297845A1 Stabilized Formulations Containing Anti-IL-33 Antibodies Public/Granted day:2020-09-24
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