Invention Grant
- Patent Title: Solubilization of antigen components for removal from tissues
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Application No.: US16912586Application Date: 2020-06-25
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Publication No.: US11596711B2Publication Date: 2023-03-07
- Inventor: Leigh G. Griffiths , Angeliki Papalamprou , Maelene L. Wong
- Applicant: The Regents of the University of California
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Foley & Lardner LLP
- Main IPC: A61L27/36
- IPC: A61L27/36 ; A61L27/38 ; A61K35/34 ; C12N5/077 ; C12N5/00
Abstract:
The present invention relates to methods for removing antigens from tissues by sequentially destabilizing and/or depolymerizing cytoskeletal components and removing and/or reducing water-soluble antigens and lipid-soluble antigens. The invention further relates to tissue scaffolding and decellularized extracellular matrix produced by such methods.
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