A quick-connection type magnetic transmission apparatus for use in a medical interventional instrument, comprising a drive-side housing and a driven-side housing. The drive-side housing and the driven-side housing are coaxially arranged and are connected in a nested mode; a magnetic coupling structure, a magnetic coupling and coaxial guiding mechanism, and an integral coaxial guiding mechanism are sequentially comprised from inside to outside; the magnetic coupling structure consists of a magnetic transmission drive end (12), a magnetic transmission driven end (11), and a quick-connection separation sleeve (13); the magnetic coupling and coaxial guiding mechanism consists of a magnetic coupling and guiding sleeve (21) and a magnetic coupling and guiding groove (22); the integral coaxial guiding mechanism consists of a coaxial guiding sleeve (31), a coaxial guiding groove (32), and a coaxial locking structure. The quick-connection type magnetic transmission apparatus for use in the medical interventional instrument uses a double guiding-locking fit structure, achieves quick connection, and ensures a minimal transmission gap.