A flow guide device of a spray container which comprises a bottle, a nozzle having a flow guide pipe and a straw is configured to be connected between the flow guide pipe and a suction pipe. The flow guide device includes a connecting pipe, a check valve and a check ball. The connecting pipe is connected with the flow guide pipe, which has a plurality of back flow passages and forward flow passages formed on the inner edge thereof. The check valve is arranged between the connecting pipe and the flow guiding pipe. The check ball is arranged in the connecting pipe and located on the port of the straw. When the spray container is in an inverted state, the liquid enters the connecting pipe, the one-way valve and the flow guide pipe from the backflow channel, and the check valve, wherein the flow guide pipe through the back flow passages is finally sprayed out. Accordingly, the flow guiding device has a simple structure and is convenient to assemble and capable of reducing the overall manufacturing costs.