A breakaway assembly including a first connector and a second connector releasably coupleable to the first connector. The assembly is movable between a first configuration in which the first and second connectors are releasably coupled and together define a fluid path through which fluid is flowable, wherein the fluid path includes an at least partially radially extending portion, and a second configuration in which the first and second connectors are not coupled together. The assembly is configured to move from the first configuration to the second configuration when a predetermined separation force is applied to the assembly. The assembly further includes a closure valve positioned in one of the first or second connectors, wherein the closure valve is configured to be in an open position when the assembly is in the first configuration to allow fluid to flow therethrough, and to move to a closed position blocking the at least partially radially extending portion of the fluid path when the assembly moves to the second configuration to generally block the flow of fluid therethrough.