Invention Grant
- Patent Title: Phosphoinositide 3-kinase inhibitors with a zinc binding moiety
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Application No.: US17585701Application Date: 2022-01-27
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Publication No.: US11597732B2Publication Date: 2023-03-07
- Inventor: Xiong Cai , Haixiao Zhai , Chengjung Lai , Changgeng Qian
- Applicant: Curis, Inc.
- Applicant Address: US MA Lexington
- Assignee: Curis, Inc.
- Current Assignee: Curis, Inc.
- Current Assignee Address: US MA Lexington
- Agency: Elmore Patent Law Group, P.C.
- Agent Edgar W. Harlan; Carolyn S. Elmore
- Main IPC: C07D495/04
- IPC: C07D495/04 ; C07D491/04 ; C07D413/14 ; A61K31/535

Abstract:
The instant application relates to deazapurines, thienopyrimidines and furopyrimidines with zinc-binding moiety based derivatives and their use in the treatment of phosphoinositide 3-kinase related diseases and disorders such as cancer. The instant application further relates to the the treatment of histone deacetylase related disorders and diseases related to both histone deacetylase and phosphoinositide 3-kinase.
Public/Granted literature
- US20220402934A1 PHOSPHOINOSITIDE 3-KINASE INHIBITORS WITH A ZINC BINDING MOIETY Public/Granted day:2022-12-22
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