Invention Grant
- Patent Title: Nicotine degrading enzyme variants
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Application No.: US16483380Application Date: 2018-02-02
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Publication No.: US11597916B2Publication Date: 2023-03-07
- Inventor: Matthew W. Kalnik , Thomas Thisted , Everett Stone , Charles C. Reed , Max Rodnick-Smith
- Applicant: ANTIDOTE THERAPEUTICS, INC. , BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- Applicant Address: US MD Sykesville; US TX Austin
- Assignee: ANTIDOTE THERAPEUTICS, INC.,BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- Current Assignee: ANTIDOTE THERAPEUTICS, INC.,BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- Current Assignee Address: US MD Sykesville; US TX Austin
- Agency: Foley & Lardner LLP
- International Application: PCT/US2018/016664 WO 20180202
- International Announcement: WO2018/144879 WO 20180809
- Main IPC: C12N9/00
- IPC: C12N9/00 ; C12N9/04 ; A61K47/60 ; A61P43/00 ; C12N9/02
Abstract:
Described are nicotine-degrading enzyme variants that exhibit increased nicotine-degrading activity and/or decreased immunogenicity relative to the wild-type NicA2 and NOX enzymes, compositions comprising the variants, and methods using them.
Public/Granted literature
- US20200224176A1 NOVEL NICOTINE DEGRADING ENZYME VARIANTS Public/Granted day:2020-07-16
Information query
