Invention Grant
- Patent Title: Combination therapy of lymphoma
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Application No.: US16758996Application Date: 2018-11-29
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Publication No.: US11597933B2Publication Date: 2023-03-07
- Inventor: Jennifer Effie Amengual , Jennifer Lue , Owen A. O'Connor
- Applicant: The Trustees of Columbia University in the City of New York
- Applicant Address: US NY New York
- Assignee: The Trustees of Columbia University in the City of New York
- Current Assignee: The Trustees of Columbia University in the City of New York
- Current Assignee Address: US NY New York
- Agency: Leason Ellis LLP
- International Application: PCT/US2018/063060 WO 20181129
- International Announcement: WO2019/108789 WO 20190606
- Main IPC: A61K35/17
- IPC: A61K35/17 ; G01N33/50 ; C12N15/113 ; A61P35/00 ; A61K31/167 ; A61K31/18 ; A61K31/4045 ; A61K31/4545 ; A61K31/496 ; A61K31/5377 ; A61K38/15
Abstract:
The present disclosure provides for methods and compositions for treating cancer. A subject having lymphoma is administered an EZH2 inhibitor and an HDAC inhibitor. The combination of the EZH2 inhibitor and the HDAC inhibitor produces a synergistic effect on the cancer compared to the effect of the EZH2 inhibitor or the HDAC inhibitor alone.
Public/Granted literature
- US20200263185A1 COMBINATION THERAPY OF LYMPHOMA Public/Granted day:2020-08-20
Information query
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