Invention Grant
- Patent Title: Methods and compositions for reducing immunosuppression by tumor cells
-
Application No.: US17102787Application Date: 2020-11-24
-
Publication No.: US11597934B2Publication Date: 2023-03-07
- Inventor: Kai W. Wucherpfennig , Glenn Dranoff , Penghui Zhou , Donald Shaffer , Nir Hacohen , Harvey I. Cantor , Diana Alvarez Arias
- Applicant: Dana-Farber Cancer Institute, Inc. , The General Hospital Corporation
- Applicant Address: US MA Boston; US MA Boston
- Assignee: Dana-Farber Cancer Institute, Inc.,The General Hospital Corporation
- Current Assignee: Dana-Farber Cancer Institute, Inc.,The General Hospital Corporation
- Current Assignee Address: US MA Boston; US MA Boston
- Agency: Crowell & Moring LLP
- Main IPC: C12N15/113
- IPC: C12N15/113 ; A61K35/17 ; C07K14/725 ; C12N5/0783 ; A61K39/00 ; C07K16/32 ; C12Q1/6886
Abstract:
The present disclosure provides, in part, methods of discovering immunotherapy targets in vivo, therapeutic compositions (e.g., shRNA, immunoresponsive cells expressing shRNA and/or a chimeric antigen receptors (CAR)), and methods of use thereof.
Public/Granted literature
- US20210139914A1 Methods and Compositions for Reducing Immunosupression by Tumor Cells Public/Granted day:2021-05-13
Information query
IPC分类:
