Invention Grant
- Patent Title: Use of ANP32 protein in maintaining the polymerase activity of influenza virus in hosts
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Application No.: US16755840Application Date: 2019-02-26
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Publication No.: US11597948B2Publication Date: 2023-03-07
- Inventor: Xiaojun Wang , Haili Zhang , Zhenyu Zhang
- Applicant: Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences (China Animal Health and Epidemiology Center, Harbin)
- Applicant Address: CN Heilongjiang
- Assignee: Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences (China Animal Health and Epidemiology Center, Harbin)
- Current Assignee: Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences (China Animal Health and Epidemiology Center, Harbin)
- Current Assignee Address: CN Heilongjiang
- Agency: Knobbe Martens Olson & Bear LLP
- Priority: CN201810177710.X 20180302
- International Application: PCT/CN2019/076171 WO 20190226
- International Announcement: WO2019/165957 WO 20190906
- Main IPC: C12N15/87
- IPC: C12N15/87 ; C07K14/435 ; C12N15/113
Abstract:
The present invention provides a recombinant sequence information of a key host factor ANP32A/B which is necessary for the replication of influenza virus in a host. More specifically, the present invention relates to a 129-130 motif and a 149 site of the host factor ANP32A/B protein, which are key active sites for exerting its ability to promote the replication of influenza virus, and are also potential targeting sites of anti-influenza drugs.
Public/Granted literature
- US20210054411A1 USE OF ANP32 PROTEIN IN MAINTAINING THE POLYMERASE ACTIVITY OF INFLUENZA VIRUS IN HOSTS Public/Granted day:2021-02-25
Information query
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