Embodiments support secure booting of an IHS (Information Handling System) based on validation of the secure assembly and delivery of the IHS. A validation process of the IHS is initialized that delays further booting of the IHS until detected hardware components of the IHS are validated. An inventory certificate is retrieved that was uploaded to the IHS during factory provisioning of the IHS. The inventory certificate includes an inventory that identifies hardware components installed during factory assembly of the IHS. A collected inventory of detected hardware components of the IHS is compared against the inventory from the inventory certificate in order to validate the detected hardware components of the IHS as the same hardware components installed during factory assembly of the IHS. When the comparison validates the detected hardware components of the IHS as only including factory assembled hardware, further booting of the IHS is allowed.