An integrated circuit including an input terminal and an output terminal, signal generator circuitry that generates a pseudo-random digital signal provided at the output terminal, and comparator circuitry that compares an input signal received via the input terminal with the pseudo-random digital signal for providing a tamper detection signal indicative thereof. The signal generator circuitry may be a pseudo-random binary sequence generator or may be a linear-feedback shift register with software triggered reloading. The comparator circuitry may include a Boolean logic exclusive-OR gate for comparing the output and input signals. A method of detecting tampering including generating and providing a pseudo-random digital signal at an output terminal and comparing an input signal received via an input terminal with the pseudo-random digital signal for providing a tamper detection signal indicative thereof.