Systems, methods, and computer-readable media are disclosed for systems and methods for autonomous device authentication and compartment unlocking. Example methods may include determining, by a user device, an identifier associated with a target Bluetooth Low Energy peripheral device, receiving a beacon from a Bluetooth Low Energy peripheral device, and determining, using the beacon, that the Bluetooth Low Energy peripheral device is the target Bluetooth Low Energy peripheral device. Example methods may include establishing a connection with the target Bluetooth Low Energy peripheral device, and sending a signal to the target Bluetooth Low Energy peripheral device to implement an action, where the signal comprises a resource identifier, and where the target Bluetooth Low Energy peripheral device controls access to a plurality of resources, and uses the resource identifier to identify a resource of the plurality of resources at which to implement the action.