An adaptive computer simulation rendering system is disclosed for conditioning an individual having Autism Spectrum Disorder (ASD) to real-world environments through variable sensory output in computer simulations. The subject is fully or partially immersed in a computer-simulated environment for a time-limited session. Real-time monitoring of the human subject is performed for a change in a sensor-derived, quantified sensory load level. Responsive to an increase in sensory load level, the computer-simulated environment modulates the sensor load on the individual. The human subject adapts to increasingly complex environments by this modulation of simulation thereby providing therapeutic benefit to the individual with ASD.