A leakage current detection and interruption (LCDI) device for a power cord includes a switch module that controls an electrical connection of first and second power supply lines between input and an output ends; a leakage current detection module, including first and second leakage current detection lines, which respectively cover the first and second power supply lines, and are respectively configured to detect leakage current signals on the first and second power supply lines and to generate self-test fault signals in response to the first and second leakage current detection lines having an open circuit; and a drive module which receives the first and/or second leakage current signal and the first and/or second self-test fault signal, and drives the switch module to disconnect the electrical connection in response to these signals. The LCDI device can individually detect leaks on the two power supply lines and open circuit on the two leakage current detection lines.