Methods and devices related to actuating an image sensor are described. In an example, a method can include generating a first image of an area at a first time using an array of image sensors, wherein each image sensor of the array of image sensors is coupled to a respective actuator, generating a second image of the area at a second time using the array of image sensors, comparing the first image to the second image using a processing resource coupled to the array of image sensors, identifying a moving object based at least in part on comparing the first image to the second image, and activating the actuator for each image sensor of the array of image sensor used to generate the first and second images based at least in part on identifying the moving object.