An electronic device includes a device housing and one or more displays presenting one or more user actuation targets defining one or more virtual buttons in a predefined arrangement relative to a first end of the device housing. One or more sensors detect a condition of the electronic device, such as an approaching object, change in the direction of gravity, or an object tapping or pushing the electronic device. One or more processors cause, in response to the one or more sensors detecting the condition, the one or more displays to present the one or more user actuation targets defining the one or more virtual buttons in another predefined arrangement that is different from the predefined arrangement.