A computer-implemented method for executing patient management workflows includes acquiring a pre-test dataset of clinically relevant information related to a patient and using a first intelligent agent to identify a diagnostic test for the patient based on the pre-test dataset. Following performance of the diagnostic test, a second intelligent agent is used to select a processing technique to be applied to data collected from the diagnostic test to obtain a diagnostic marker. Following application of the processing technique to the data collected from the diagnostic test, a third intelligent agent is used to generate an optimal patient management plan based on the pre-test dataset, the data collected from the diagnostic test, and the diagnostic marker.