Invention Grant
- Patent Title: Inhibition of dipeptide repeat proteins
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Application No.: US16895875Application Date: 2020-06-08
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Publication No.: US11607402B2Publication Date: 2023-03-21
- Inventor: Fernando G. Vieira , Alan Premasiri , Anna Gill
- Applicant: ALS Therapy Development Institute
- Applicant Address: US MA Cambridge
- Assignee: ALS Therapy Development Institute
- Current Assignee: ALS Therapy Development Institute
- Current Assignee Address: US MA Cambridge
- Agency: Nelson Mullins Riley & Scarborough LLP
- Agent Jeanne M. DiGiorgio, Esq.
- Main IPC: A61K31/40
- IPC: A61K31/40 ; A61K31/4155 ; A61K31/4545 ; A61K31/428 ; A61K45/06
Abstract:
Methods are disclosed for treating neurodegenerative disorders, such as ALS and FTD by using an effective amount of a type I protein arginine methyltransferase (Type I PRMT) inhibitor to decrease cellular toxicity caused by dipeptide repeat proteins (DRPs).
Information query
