Invention Grant
- Patent Title: Synergistic effects between auristatin-based antibody drug conjugates and inhibitors of the PI3K-AKT mTOR pathway
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Application No.: US16226509Application Date: 2018-12-19
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Publication No.: US11607460B2Publication Date: 2023-03-21
- Inventor: Timothy S. Lewis , Che-Leung Law , Julie A. McEarchern
- Applicant: SEATTLE GENETICS, INC.
- Applicant Address: US WA Bothell
- Assignee: SEATTLE GENETICS, INC.
- Current Assignee: SEATTLE GENETICS, INC.
- Current Assignee Address: US WA Bothell
- Agency: Alston & Bird LLP
- Main IPC: A61K31/436
- IPC: A61K31/436 ; A61P35/00 ; A61K47/68 ; A61K45/06 ; A61K31/4375 ; A61K31/4745 ; A61K31/498 ; A61K31/519 ; A61K31/5377 ; A61K39/395
Abstract:
The present invention is directed to methods for treating cancer comprising administering to a subject in need thereof an auristatin-based antibody drug conjugate and an inhibitor of the PI3K-AKT-mTOR pathway.
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