Invention Grant
- Patent Title: Oxazolidinone hydroxamic acid derivatives
-
Application No.: US17145357Application Date: 2021-01-10
-
Publication No.: US11608320B2Publication Date: 2023-03-21
- Inventor: Charles Ifeamalume Ezeamuzie , Oludotun Adebayo Phillips
- Applicant: KUWAIT UNIVERSITY
- Applicant Address: KW Safat
- Assignee: KUWAIT UNIVERSITY
- Current Assignee: KUWAIT UNIVERSITY
- Current Assignee Address: KW Safat
- Agency: Nath, Goldberg & Meyer
- Agent Richard C. Litman
- Main IPC: C07D263/06
- IPC: C07D263/06 ; A61P11/06 ; A61P37/08 ; A61K31/421

Abstract:
Oxazolidinone hydroxamic acid derivatives of the general formula (I): where R1 is hydrogen or hexanoyl and R2 is amino, methyl, ethyl, propyl, isopropyl, cyclopropyl, butyl, isobutyl, cyclobutyl, pentyl, cyclopentyl, hexyl or heptyl, and pharmaceutically acceptable salts thereof, act as dual inhibitors of 5-lipoxygenase and mast cell degranulation. The oxazolidinone hydroxamic acid derivatives or pharmaceutically acceptable salts thereof can be used in the prevention and treatment of asthma and allergies, as well as inflammatory conditions.
Public/Granted literature
- US20210238151A1 OXAZOLIDINONE HYDROXAMIC ACID DERIVATIVES Public/Granted day:2021-08-05
Information query