Invention Grant
- Patent Title: Tumor-targeted agonistic CD28 antigen binding molecules
-
Application No.: US16721272Application Date: 2019-12-19
-
Publication No.: US11608376B2Publication Date: 2023-03-21
- Inventor: Guy Georges , Thomas Hofer , Ralf Hosse , Christian Klein , Ekkehard Moessner , Johannes Sam , Pablo Umaña , Jenny Thom , Stephan Gasser , Jean-Baptiste Vallier , Tanja Fauti
- Applicant: Hoffmann-La Roche Inc.
- Applicant Address: US NJ Little Falls
- Assignee: Hoffmann-La Roche Inc.
- Current Assignee: Hoffmann-La Roche Inc.
- Current Assignee Address: US NJ Little Falls
- Agent Yan Qi
- Priority: EP18215121 20181221,EP19187709 20190723,EP19196006 20190906
- Main IPC: C07K16/28
- IPC: C07K16/28 ; C07K16/30 ; C07K16/32 ; C07K16/40 ; A61P35/00 ; A61K39/00
Abstract:
The present invention relates to tumor targeted bispecific agonistic antigen binding molecules characterized by monovalent binding to CD28, methods for their production, pharmaceutical compositions containing these antibodies, and methods of using the same.
Information query
