An indoor air quality (IAQ) system for a building includes an IAQ sensor that is located within the building and that is configured to measure an IAQ parameter. The IAQ parameter is one of: an amount of particulate of at least a predetermined size present in air; an amount of volatile organic compounds (VOCs) present in air; and an amount of carbon dioxide present in air. A mitigation module is configured to: selectively turn on a mitigation device based on a comparison of the IAQ parameter with a first ON threshold and a second ON threshold; and selectively turn off the mitigation device based on a comparison of the IAQ parameter with an OFF threshold. A clean module is configured to determine a clean value for the IAQ parameter. A thresholds module is configured to, based on the clean value, determine the first ON threshold and the OFF threshold.