An integrated circuit in a transmitter includes a multi-lane interface, N signal generating circuits, a lane selection circuit and a control circuit. The multi-lane interface has N lanes. M of the N signal generating circuits are configured to generate M clock signals respectively. (N-M) of the N signal generating circuits are configured to generate (N-M) data signals respectively. The lane selection circuit is configured to select M of the N lanes as M clock lanes by coupling the M clock signals to the M clock lanes respectively, and couple one of the (N-M) data signals to one of remaining (N-M) lanes, serving as (N-M) data lanes, according to a data select signal. The control circuit is configured to generate a data select signal according to a lane identifier of the one of the (N-M) lanes. The data select signal has a signal value mapping to the lane identifier.