A polyhedral LED display screen is provided and includes multiple cabinet main frames. Each the cabinet main frame is formed with an accommodating cavity. A side of each cabinet main frame is provided with a flexible PCB, an outer side of the flexible PCB facing away from the cabinet main frame is disposed with LED lamp beads, an inner side of the flexible PCB facing towards the cabinet main frame is magnetically connected to the cabinet main frame, and the cabinet main frames are connected to each other to form a regular dodecahedron sphere. The multiple cabinet main frames can be completely covered by the flexible PCBs, a missing display at an end point in the prior art is eliminated, design numbers and complexities of the cabinet main frames and the flexible PCBs are reduced, and an installation of the cabinet main frames becomes more convenient.