Invention Grant
- Patent Title: PSMA binding antibody and uses thereof
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Application No.: US16069656Application Date: 2017-01-16
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Publication No.: US11612646B2Publication Date: 2023-03-28
- Inventor: Helmut Salih , Fabian Vogt , Gundram Jung , Latifa Zekri-Metref
- Applicant: Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts , Eberhard Karls Universität Tübingen
- Applicant Address: DE Heidelberg; DE Tübingen
- Assignee: Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts,Eberhard Karls Universität Tübingen
- Current Assignee: Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts,Eberhard Karls Universität Tübingen
- Current Assignee Address: DE Heidelberg; DE Tübingen
- Agency: Foley Hoag LLP
- Agent N. Scott Pierce
- Priority: EP16151281 20160114
- International Application: PCT/EP2017/050834 WO 20170116
- International Announcement: WO2017/121905 WO 20170720
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/28 ; A61K39/00 ; C07K16/30 ; A61P35/00
Abstract:
The present invention provides a novel PSMA binding antibody termed 10B3 and pharmaceutical and diagnostic uses of the antibody 10B3. The PSMA antibody 10B3 does not cross-compete with the state of the art PMSA binding antibody J591 and has a reduced induction of antigen shift compared to J591 and a unique reactivity with squamous cell carcinoma (SCC) cells of different origin.
Public/Granted literature
- US20190022205A1 PSMA Binding Antibody and Uses Therof Public/Granted day:2019-01-24
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