Invention Grant
- Patent Title: Process for the preparation of drug linker compounds
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Application No.: US16768027Application Date: 2018-11-29
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Publication No.: US11612666B2Publication Date: 2023-03-28
- Inventor: Sophie Blanchard , James Coats
- Applicant: Seagen Inc.
- Applicant Address: US WA Bothell
- Assignee: Seagen Inc.
- Current Assignee: Seagen Inc.
- Current Assignee Address: US WA Bothell
- Agency: Morrison & Foerster LLP
- International Application: PCT/US2018/063070 WO 20181129
- International Announcement: WO2019/108797 WO 20190606
- Main IPC: A61K47/65
- IPC: A61K47/65 ; C07D403/12 ; C07D471/04 ; C07K1/10 ; C07K5/02 ; C07K7/02 ; A61K47/68 ; C07K5/062
Abstract:
This disclosure generally relates to novel processes for the preparation of drug linker compounds and compositions comprising such drug linker compounds. The presently disclosed methods for synthesizing Fmoc-Val-Cit-PABOH and related compounds have also been found to minimize formation of diastereomeric impurities.
Public/Granted literature
- US1676204A Oil still Public/Granted day:1928-07-03
Information query
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