A device for cosmetic treatment, in particular for permanent make-up, micro-needling or micro-pricking treatments, including a body having a first section, arranged at a first end of the body, in which a drive motor of the device (1) is arranged, a second section, arranged at a second end of the body, opposite the first end, in which a needle-holding cartridge can be fitted, and a third section, that connects the first section to the second section, in which drive means is housed of the needles contained in said needle-holding cartridge. The needle-holding cartridge includes a support element configured for supporting a single needle, or a plurality of needles and is movable inside a casing. of the cartridge The needle-holding cartridge is driven to move inside the casing by the drive means between a variable start position and a variable end position for a preset distance.