Provided is a pneumatic tire having both improved run-flat durability and excellent wet grip properties; the pneumatic tire including a rubber composition used in a tread part, and a rubber support layer having a gauge thickness in a specified range; the rubber composition including specified compounded amounts of natural rubber, a terminal-modified styrene-butadiene rubber, silica, and a thermoplastic resin, wherein the rubber composition is largely strain-dependent for the storage elastic modulus.