Invention Grant
- Patent Title: Macrocyclic compound serving as Wee1 inhibitor and applications thereof
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Application No.: US16759769Application Date: 2018-10-31
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Publication No.: US11613545B2Publication Date: 2023-03-28
- Inventor: Wenyuan Qian , Chundao Yang , Zhengwei Li , Jie Li , Jian Li , Shuhui Chen
- Applicant: WUXI BIOCITY BIOPHARMACEUTICS CO., LTD.
- Applicant Address: CN Jiangsu
- Assignee: WUXI BIOCITY BIOPHARMACEUTICS CO., LTD.
- Current Assignee: WUXI BIOCITY BIOPHARMACEUTICS CO., LTD.
- Current Assignee Address: CN Jiangsu
- Agency: Harness, Dickey & Pierce, P.L.C.
- Priority: CN201711058653.5 20171101
- International Application: PCT/CN2018/112909 WO 20181031
- International Announcement: WO2019/085933 WO 20190509
- Main IPC: C07D487/14
- IPC: C07D487/14 ; A61P35/04 ; C07D519/00

Abstract:
Disclosed in the present invention are a macrocyclic compound serving as a Weel inhibitor, and applications thereof in the preparation of drugs for treating Weel-related diseases. The present invention specifically relates to a compound represented by formula (II), an isomer thereof, and a pharmaceutically acceptable salt thereof.
Public/Granted literature
- US20200325145A1 MACROCYCLIC COMPOUND SERVING AS WEE1 INHIBITOR AND APPLICATIONS THEREOF Public/Granted day:2020-10-15
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