Invention Grant
- Patent Title: Combination therapy of T cell activating bispecific antigen binding molecules and PD-1 axis binding antagonists
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Application No.: US16988540Application Date: 2020-08-07
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Publication No.: US11613587B2Publication Date: 2023-03-28
- Inventor: Christian Klein , Vaios Karanikas , Pablo Umana , Alfred Zippelius , Daniela Stefanie Thommen , Jens Schreiner
- Applicant: Hoffmann-La Roche Inc.
- Applicant Address: US NJ Little Falls
- Assignee: Hoffmann-La Roche Inc.
- Current Assignee: Hoffmann-La Roche Inc.
- Current Assignee Address: US NJ Little Falls
- Agency: Clark & Elbing LLP
- Agent Karen L. Elbing
- Priority: EP14194136 20141120,EP15152141 20150122,EP15167173 20150511
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C07K16/30 ; C07K16/28 ; A61K47/68 ; C07K16/46 ; A61K39/00
Abstract:
The present invention generally relates to T cell activating bispecific antigen binding molecules, PD-1 axis binding antagonists, and in particular to combination therapies employing such T cell activating bispecific antigen binding molecules and PD-1 axis binding antagonists, and their use of these combination therapies for the treatment of cancer.
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